In this paper, we report development of a kretschmann configuration based spr. Osa sidepolished fewmode fiber based surface plasmon. It is the fundamental principle behind many colorbased biosensor applications, different labonachip sensors and diatom photosynthesis. Besides being bulky, the prismbased spr sensors have the. Surface plasmon resonance spr sensing has been demonstrated in the past. Surface plasmon resonance spr based biosensors are the most advanced and developed optical labelfree biosensor technique used for powerful detection with vast applications in environmental protection, biotechnology, medical diagnostics, drug screening, food safety, and security as well in livestock sector. Surface plasmon resonance based sensors jiri homola springer. Surface plasmon resonancebased sensing utilizing spatial phase modulation in an imaging interferometer view fulltext download pdf spatial phase modulation in an imaging interferometer is utilized in surface plasmon resonance spr based sensing of liquid analytes. The sensor is designed to detect low refractive indexes between 1. Some other surface effects such as surfaceenhanced raman scattering and surfaceenhanced fluorescence are induced by surface plasmon of noble metals, therefore sensors based on surface plasmons were developed. A surface plasmon based chemooptical sensor has been optimized by the use of computer simulation programs. The principle that is used in surface plasmon resonance spr sensors is to measure the changes in the refractive. Miniaturized surface plasmon resonance based sensor system.
Plasmon means the quasiparticle representation of plasma frequency. The design of a fibre optic surface plasmon resonance spr sensor based on silvergold alloy nanoparticle film is studied. The response theory of the absorptionbased spr sensing is based on the expansion of kretchmanns spr theory into the case in which optical absorption in the. Surface plasmon resonance based sensors springer series on chemical sensors and biosensors.
Kabashin, plasmon excitation by the gaussianlike core mode of a photonic crystal. Spr is the basis of many standard tools for measuring adsorption of material onto planar metal surfaces or onto the surface of metal nanoparticles. Background surface plasmon resonance spr sensing has been demonstrated in the past decade to be an exceedingly powerful and quantitative probe of the interactions of a variety of biopolymers with. Polymerbased chips for surface plasmon resonance sensors. An opticalabsorptionbased surface plasmon resonance spr sensor is proposed, and its theoretical aspects are discussed in terms of mathematical descriptions and numerical simulations of the spr curve. A surface plasmon resonance spr sensor with two openring channels based on a photonic crystal fiber pcf is described. Photonic bandgap fiberbased surface plasmon resonance sensors. Noble metal nanoparticlebased localized surface plasmon resonance lspr is an advanced and powerful labelfree biosensing technique which is wellknown for its high sensitivity to the surrounding refractive index change in the local environment caused by the biomolecular interactions around the sensing area. Part i introduces readers to the fundamental principles of surface plasmon resonance biosensors and covers the electromagnetic theory of surface plasmons, the theory of spr sensors and molecular interactions at sensor surfaces. Fiberoptic sensors based on surface plasmon resonance. Cortie institute for nanoscale technology, university of technology sydney, po. Because of low coupling efficiency of conventional methods, usually intricate. To solve the problem of air hole coating and analyte filling in microstructured optical fiberbased surface plasmon resonance spr sensors, we designed an exposedcore grapefruit fiber ecgfsbased spr sensor. Homola j ed surface plasmon resonance based sensors.
In surface second harmonic generation, the second harmonic signal is proportional to the square of the electric field. A surface plasmon resonance spr refractive index sensor for liquids was fabricated and characterized. We demonstrate that by judicious design of the photonic crystal reflector, the effective refractive. Surface plasmon resonance technique in collaboration with optical fiber technology has brought tremendous advancements in sensing of various physical, chemical, and biochemical parameters. The fiber geometry, fiber parameters and modeguiding properties are crucial for realizing highperformance fiberbased sensors. The lightweight optical components and sensing element are connected by optical fibers on a.
Surface plasmon resonancebased fiber and planar waveguide sensors. Surface plasmon resonance biosensor based on smart phone. Surface plasmon resonance sensor based on photonic crystal. We propose a novel localized surface plasmon resonance lspr sensor system based on polymer material. Nanoparticles are of interest to the scientific community for a multitude of reasons including their large surface area to volume ratio which makes them very reactive to external stimuli quickly, the fact that they operate on a quantum mechanics scale, and because the nanoscale is the level at which many biological. However, to select the monitoring wavelength, monodisperse.
Issuu is a digital publishing platform that makes it simple to publish magazines, catalogs, newspapers, books, and more online. Surface plasmon resonance spr is used in sensing applications for medical diagnostics, food safety and biodefense, environmental monitoring, the pharmaceutical industry and industrial process control. Surface plasmon resonance spr biosensor development charles t. A surface plasmon resonance based integrated optical sensor. A novel photonic crystal fiber pcf sensor composed of an indium tin oxide ito coating on the outer surface based on surface plasmon resonance pcfspr is designed and investigated. In 19721974, he was a nih special research fellow, and since 1979, he has been an ieee fellow.
Surface plasmon resonance sensor based on resonant interaction between a guided mode of a singlemode optical fiber and a surface plasmon wave supported by. Since the introduction of optical fiber technology in the field of sensor based on the technique of surface plasmon resonance spr, fiberoptic spr sensors have witnessed a lot of advancements. Over the last two decades, surface plasmon resonance spr sensors have. The advances in waveguide spp sensors will certainly have an impact in reducing costs of traditionally expensive surface plasmon resonance sensor instruments, based, for example, on the highly reliable kretchmann technique, and therefore should be available commercially in the near future. We demonstrate a fiber optic surface plasmon resonance spr biosensor based on smart phone platforms. Surface plasmon resonance based sensors ebook, 2006. Ultrasensitive detection of mirna with an antimonenebased. Spr technique has been very promising for sensing applications. Surface plasmon resonance based sensors jiri homola.
Surface plasmon resonance spr biosensor development a. Over the last two decades, surface plasmon resonance spr sensors have attracted a great deal of attention. Basic principles of spr when monochromatic, polarised light hits an interface of two transparent media, such as a glass prism and a buffer solution, from the side of the media with the highest refractive index glass prism, the light is partly reflected and partly refracted towards the plane of the interface. In 1993 he joined the institute of radio engineering and electronics of the academy of sciences of the czech republic, prague, as a research scientist, working on fiber optic sensors and surface plasmon resonancebased sensing devices. Due to its many advantages, such as nondestructive labelfree detection, high reproducibility and low cost, the surface plasmon resonance spr technique has proven to be versatile in investigations of molecular interactions by assessing the refractive index change on a chip surface 9 11. Surface plasmon resonance spr sensors springerlink. High sensitivity surface plasmon resonance sensor based on. The surface plasmon resonance corresponds to an evanescent wave at the interface of a metal and a dielectric, which is due to a collective excitation of the electrons at the surface of the metal. The aim of this work is to measure the temperature variations by analyzing the plasmon signature on a metallic surface that is periodically structured and immersed in a liquid. As the signals of potentiometricbased dna ionselective field effect transistor isfet sensors differ largely from report to report, a systematic revisit to this method is needed. Surface plasmon resonance spectroscopy, sensor, sprimaging, miniaturization, microoptoelectro. The fmfspr sensor was fabricated via sidepolishing a fewmode fiber and coating a thin layer of gold film, on the basis. Sensors free fulltext surface plasmon resonancebased.
His main research interests are concerned with siliconbased and gaas quantum well optical modulator devices, surface plasmon resonance, as well as microsensor arrays. Surface plasmon resonance spr is employed as one of the key phenomena in biological, chemical and gas sensors. Abstract surface plasmon resonance spr based biosensors are the most advanced and developed optical labelfree biosensor. In such sensors, plasmons on the inner surface of the large metallized channels containing analyte can be excited by a fundamental mode of a singlemode microstructured. Our sensor is based on surface plasmon resonance spr and overcomes many of the limitations of the sensors proposed to date. This volume of springer series on chemical sensors and biosensors provides a comprehensive treatment of the field of spr sensors. Successful production of a largearea mos2 monolayer blocks the penetration of oxygen and. Novel surface plasmon resonance sensor based on single. It is a safe and rapidresponse device that can be used in inflammable or explosive environments such as fuel tanks, as opposed to capacitance sensors or those based on electrodes. Pdf surface plasmon resonancebased fiber and planar. The performance of the proposed sensor is theoretically analysed in terms of its signaltonoise ratio snr and sensitivity under different conditions related to the metal layer with silver and gold nanoparticles embedded together in. Localized surface plasmon resonance sensors based on. Localized surface plasmon resonance lspr sensors serve as sensitive analytical tools based on refractive index changes, which can be applied to affinitybased chemical sensing and biosensing. A change in the temperature of the sample surface induces a modification of the local refractive index leading to a shift of the surface plasmon resonance spr frequency due to the strong.
Over the last two decades, surface plasmon resonance spr sensors have attracted a great. Request pdf surface plasmon resonance based sensors fundamentals of spr sensors. Optical sensors based on surface plasmon resonance spr has been widely used for biosensing and chemical sensing in the past few decades due to their superior characteristics, such as being highly sensitive, reliable, labelfree, and their capacity for realtime detection 15. Surface plasmon resonance based sensors request pdf.
This volume of springer series on chemical sensors and biosensors provides a comprehensive. Sensors free fulltext surface plasmon resonance based. Optimization of a chemooptical surface plasmon resonance based. Easily share your publications and get them in front of issuus.
A new platform for rapid diagnosis of livestock diseases, veterinary world, 912. A change in the temperature of the sample surface induces a modification of the local refractive index leading to a shift of the surface plasmon resonance spr frequency due to the strong interaction. Theoretical understanding of an absorptionbased surface. Characteristics of multiple fano resonances in waveguidecoupled surface plasmon resonance sensors based on waveguide theory skip to main content thank you for visiting. This paper reports on the past, present, and future scope of fiberoptic spr sensors in the field of sensing of different chemical, physical, and biochemical.
Highly sensitive graphene biosensors based on surface plasmon resonance. The sensor consists of eight air holes arranged in a rectangular grid as the cladding, the ito layer as the plasmonic materials, and an annular external channel. To overcome this limitation, we fabricated the planar plasmonic substrate employing an atomic mos2 layer on a silver surface. Surface plasmon resonance technique in collaboration with optical fiber technology has brought tremendous advancements in sensing of various physical. Sensors based on monochromatic interrogation of a localised surface plasmon resonance catherine s. The exposed section of the ecgf is coated with a spr, supporting thin silver film, which can sense the analyte in the external environment. This paper reports on the past, present, and future. An exposedcore grapefruit fibers based surface plasmon. Gold nanorodbased localized surface plasmon resonance. Surface plasmon resonance based refractive index sensor. Sensitivity and stability enhancement of surface plasmon.
Plasmon wave on the surface of a thin metal film embedded into a fiber microstructure is excited by a leaky gaussianlike core mode of a fiber. Highly sensitive graphene biosensors based on surface. Fabrication and measurement of optical waveguide sensor. Currently he is a visiting scientist at the university of washington, seattle.
Surface plasmon resonance based sensors springerlink. Estimating detection limits of potentiometric dna sensors. Skorobogatiy, design criteria for the microstructured optical fiberbased surface plasmon resonance sensors, accepted for publication in the j. Surface plasmon resonance is the resonant oscillation of conduction electrons at the interface between negative and positive permittivity material stimulated by incident light. The concept of photonic bandgap fiberbased surface plasmon resonance sensor operating with low refractive index analytes is developed. The proposed lspr system consists of the incident medium with lowloss polymer waveguide and the chemically immobilized plasmonic nanoparticles for onchip lspr sensing. Homola j 2006 electromagnetic theory of surface plasmons. The surface plasmon is the plasma oscillation that localize at the surface or interface. Surface plasmon resonance spr sensors based on a silver film suffer from signal degradation due to silver oxidation in aqueous sensing environments. Osa midinfrared surface plasmon resonance sensor based. Surface plasmon resonance based sensors springer series. Fibreoptic sensor based on surface plasmon resonance with. Herein, the hybridization of the target and the probe dna on the sensor surface and its dependence on the surface probe dna coverage and the ionic strength were systematically investigated by.